SCHEMBL8722310

SCHEMBL8722310

Cc1cc(C2=CC=CC(C)(N)C2)ccc1N

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
CYP3A4 P08684 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
TSHR P16473 1/20 0.48
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
APP P05067 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
ALOX12 P18054 1/20 0.31
HAVCR2 Q8TDQ0 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
S100B P04271 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990190 0.75
SCHEMBL3662419 0.73 CA12 (0.35) ALDH1A1CYP3A4TDP1SMN1; SMN2APP
Orthotolidine SCHEMBL29386552 0.69 CYP3A4 (1.00) ALDH1A1CYP3A4TDP1TSHRNPC1
Orthotolidine SCHEMBL29365329 0.69 CYP3A4 (1.00) ALDH1A1CYP3A4TDP1TSHRNPC1
Orthotolidine SCHEMBL49414 0.69 CYP3A4 (1.00) ALDH1A1CYP3A4TDP1TSHRNPC1
SCHEMBL8720897 0.67 ALDH1A1 (0.50) ALDH1A1CYP3A4TDP1TSHRKDM4E
SCHEMBL18967510 0.67 CYP3A4 (0.55) ALDH1A1CYP3A4TDP1TSHRNPC1
SCHEMBL102613 0.67 ALDH1A1 (0.50) ALDH1A1CYP3A4TDP1TSHRNPC1
Orthotolidine SCHEMBL6009632 0.67 CYP3A4 (0.94) ALDH1A1CYP3A4TDP1TSHRNPC1
Orthotolidine SCHEMBL2812115 0.67 CYP3A4 (0.94) ALDH1A1CYP3A4TDP1TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210139390-A1 PRODUCTION METHOD OF ORGANIC COMPOUND UNITIKA LTD. (JP) 2021-05-13 US disclosed
EP-3819283-A1 METHOD FOR PRODUCING ORGANIC COMPOUND Unitika Ltd. (JP) 2021-05-12 EP disclosed
WO-2020009016-A1 METHOD FOR PRODUCING ORGANIC COMPOUND ユニチカ株式会社 2020-01-09 WO disclosed
EP-0648796-B1 Solutions of polyimide-forming substances and their use SCHENECTADY INT INC (US) 1998-08-26 EP disclosed
EP-0543409-B1 Insulated wire SUMITOMO ELECTRIC INDUSTRIES (JP) 1996-07-17 EP disclosed
US-5493003-A MIXTURES OF AMINES, AMIDES AND/OR ESTERS OF TETRACARBOXYLIC ACIDS HAVING AMIDO OR ESTER GROUPS SUBSTITUTED WITH CARBOXYL, SULFO, SILYL OR SILOXY GROUPS, ELECTRONICS BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1996-02-20 US disclosed
US-5478917-A Aromatic polyamines, tetracarboxylic acid amides and esters; smoothness, flexibility BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1995-12-26 US disclosed
US-5474876-A Carboxyl-containing polymeric precursor of heterocyclic polymer which is stable at high temperatures and soluble in polar solvents, copolymerizable unsaturated tertiary sulfonium salt, photoinitiator, polar aprotic organic solvent BASF LACKE + FARBEN AG (DE) 1995-12-12 US disclosed
EP-0648796-A1 Solutions of polyimide-forming substances and their use BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0648795-A1 Solutions of polyimide-forming substances and their use as coating material BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0571899-B1 Radiation-curable mixture and its' use for producing high temperature-resistant relief structures BASF LACKE & FARBEN (DE) 1994-11-02 EP disclosed
EP-0573866-B1 Method for forming patterned layers of heat-resistant polycondensates BASF LACKE & FARBEN (DE) 1994-11-02 EP disclosed
US-5356708-A Conductor and insulating coating made from polyamideimide base coating SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1994-10-18 US disclosed
US-5350663-A Construction of electrical circuits and protective or insulating layers for electronic components BASF LACKE+ FARBEN AKTIENGESELLSCHAFT (DE) 1994-09-27 US disclosed
EP-0573866-A1 Method for forming patterned layers of heat-resistant polycondensates BASF Lacke + Farben Aktiengesellschaft (DE) 1993-12-15 EP disclosed
EP-0571899-A1 Radiation-curable mixture and its' use for producing high temperature-resistant relief structures BASF Lacke + Farben Aktiengesellschaft (DE) 1993-12-01 EP disclosed