Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720919 | 0.85 | MAPT (0.46) | MEN1KMT2ANPSR1CYP3A4CYP2C9 | |
| SCHEMBL8726103 | 0.78 | MEN1 (0.49) | MEN1KMT2AALOX15TSHRUSP2 | |
| SCHEMBL8720881 | 0.77 | MEN1 (0.47) | MEN1KMT2AALOX15TSHRUSP2 | |
| SCHEMBL8724216 | 0.76 | CYP11B1 (0.42) | MEN1KMT2AALOX15TSHRUSP2 | |
| SCHEMBL27457703 | 0.72 | MEN1 (0.60) | MEN1KMT2AALOX15TSHRLMNA | |
| SCHEMBL27958208 | 0.67 | CYP11B1 (0.54) | MEN1KMT2AALOX15TSHRUSP2 | |
| Pyridine SCHEMBL30984530 | 0.67 | CYP3A4 (0.70) | MEN1KMT2ANPSR1TDP1CYP11B1 | |
| SCHEMBL8724176 | 0.65 | CYP1A2 (0.38) | MEN1KMT2AALOX15TSHRCYP11B1 | |
| SCHEMBL28084001 | 0.65 | TSHR (0.58) | MEN1KMT2AALOX15TSHRUSP2 | |
| SCHEMBL31124 | 0.64 | CYP3A4 (0.58) | MEN1KMT2ATDP1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |