Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722162 | 0.85 | PKM (0.36) | MAPTNPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL8722319 | 0.85 | MEN1 (0.42) | MEN1KMT2ACYP3A4CYP2C9NPSR1 | |
| SCHEMBL8726099 | 0.83 | PKM (0.41) | MAPTNPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL8722148 | 0.82 | CHRNB2 (0.41) | MAPTNPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL8722302 | 0.76 | MGAM (0.42) | MAPTNPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL403505 | 0.74 | MAPT (0.64) | MAPTNPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL2627217 | 0.68 | IDO1 (0.59) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL8724216 | 0.68 | CYP11B1 (0.42) | MAPTNPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL8726103 | 0.65 | MEN1 (0.49) | MAPTCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL2179103 | 0.64 | APP (0.66) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |