Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719239 | 0.89 | KDM4E (0.62) | KMT2AALDH1A1MAPTMEN1HTR1A | |
| SCHEMBL8722372 | 0.88 | KDM4E (0.63) | KMT2AALDH1A1MEN1HTR1AKDM4E | |
| SCHEMBL8901810 | 0.87 | MAPT (0.67) | KMT2AALDH1A1NPC1MAPTTSHR | |
| SCHEMBL8722760 | 0.87 | MAPT (0.67) | KMT2AALDH1A1NPC1MAPTTSHR | |
| SCHEMBL8719441 | 0.86 | HTR1A (0.64) | KMT2AALDH1A1MEN1HTR1AKDM4E | |
| SCHEMBL8719497 | 0.86 | HTR1A (0.64) | KMT2AALDH1A1MEN1HTR1AKDM4E | |
| SCHEMBL8719240 | 0.83 | HTR2A (0.55) | KMT2AALDH1A1MEN1HTR1AKDM4E | |
| SCHEMBL8916658 | 0.82 | MAPT (0.73) | KMT2AALDH1A1NPC1MAPTTSHR | |
| SCHEMBL8893026 | 0.79 | ALDH1A1 (0.56) | KMT2AALDH1A1MEN1HTR1AKDM4E | |
| SCHEMBL8894896 | 0.78 | ALDH1A1 (0.57) | KMT2AALDH1A1MEN1HTR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042692-A1 | PIPERAZINES DERIVED FROM CYCLIC AMINES, PREPARATION AND APPLICATION THEREOF AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-10-01 | — | — | WO | disclosed |