Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | HTR5A | P47898 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719239 | 0.99 | KDM4E (0.62) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8722375 | 0.88 | KMT2A (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8719240 | 0.87 | HTR2A (0.55) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8722757 | 0.84 | DRD2 (0.65) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8724506 | 0.83 | HTR1A (0.67) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8902187 | 0.83 | HTR1A (0.67) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8901177 | 0.83 | HTR1A (0.67) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8719445 | 0.83 | ALDH1A1 (0.72) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8720336 | 0.83 | ALDH1A1 (0.72) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8724501 | 0.83 | ALDH1A1 (0.72) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042692-A1 | PIPERAZINES DERIVED FROM CYCLIC AMINES, PREPARATION AND APPLICATION THEREOF AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-10-01 | — | — | WO | disclosed |