Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893026 | 0.99 | ALDH1A1 (0.56) | ALDH1A1KDM4ETDP1AVPR2AVPR1A | |
| SCHEMBL26473594 | 0.96 | ALDH1A1 (0.55) | ALDH1A1KDM4ETDP1AVPR2AVPR1A | |
| SCHEMBL26473528 | 0.84 | DRD2 (0.56) | ALDH1A1KDM4ETDP1DRD2DRD3 | |
| SCHEMBL1307818 | 0.83 | DRD2 (0.58) | ALDH1A1KDM4ETDP1DRD2DRD3 | |
| SCHEMBL8722757 | 0.83 | DRD2 (0.65) | ALDH1A1KDM4ETDP1AVPR2AVPR1A | |
| SCHEMBL8724506 | 0.82 | HTR1A (0.67) | ALDH1A1KDM4ETDP1AVPR2AVPR1A | |
| SCHEMBL8901177 | 0.82 | HTR1A (0.67) | ALDH1A1KDM4ETDP1AVPR2AVPR1A | |
| SCHEMBL8902187 | 0.82 | HTR1A (0.67) | ALDH1A1KDM4ETDP1AVPR2AVPR1A | |
| SCHEMBL8722372 | 0.81 | KDM4E (0.63) | ALDH1A1KDM4ETDP1DRD2DRD3 | |
| SCHEMBL8714738 | 0.81 | AVPR2 (0.56) | ALDH1A1KDM4ETDP1AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014689-A1 | ARYL-PIPERAZINE CYCLIC AMINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | PIERRE FABRE MEDICAMENT (FR) | 1997-04-24 | — | — | WO | disclosed |