Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726191 | 0.91 | CA2 (0.41) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL8726236 | 0.87 | TAS1R3 (0.40) | TAS1R3TAS1R1 | |
| SCHEMBL8722086 | 0.84 | CA2 (0.42) | PYGLCA12CA1CA2CA9 | |
| SCHEMBL8724198 | 0.81 | TAS1R3 (0.37) | TAS1R3TAS1R1 | |
| SCHEMBL8722941 | 0.80 | CA2 (0.41) | CA12CA1CA2CA9TYMS | |
| SCHEMBL8722147 | 0.78 | CA2 (0.39) | TAS1R3TAS1R1CA12CA1CA2 | |
| SCHEMBL8722158 | 0.77 | CA2 (0.41) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL8722146 | 0.77 | CA1 (0.43) | TAS1R3TAS1R1CA12CA1CA2 | |
| SCHEMBL8726202 | 0.77 | CA2 (0.46) | CA12CA1CA2CA9TYMS | |
| SCHEMBL8722082 | 0.76 | CA1 (0.42) | TAS1R3TAS1R1PYGLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | claimed |
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |