Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724221 | 0.87 | CA1 (0.42) | CA2CA1CA12CA9UTS2R | |
| SCHEMBL8722941 | 0.84 | CA2 (0.41) | CA2CA1CA12CA9LMNA | |
| SCHEMBL8726191 | 0.84 | CA2 (0.41) | CA2CA1CA12CA9FOLH1 | |
| SCHEMBL8722086 | 0.84 | CA2 (0.42) | CA2CA1CA12CA9PRSS1 | |
| SCHEMBL8726202 | 0.83 | CA2 (0.46) | CA2CA1CA12CA9LMNA | |
| SCHEMBL8722982 | 0.80 | MMP2 (0.50) | CA2CA1CA12CA9PRSS1 | |
| SCHEMBL8726177 | 0.79 | ALDH1A1 (0.37) | TDP1UTS2R | |
| SCHEMBL8722628 | 0.77 | MMP2 (0.37) | CA2CA1CA12CA9MMP2 | |
| SCHEMBL8722107 | 0.77 | PYGL (0.36) | CA2CA1CA12CA9LMNA | |
| SCHEMBL8722082 | 0.75 | CA1 (0.42) | CA2CA1CA12CA9FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |