Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722961 | 0.90 | CA2 (0.46) | CA2CA1CA12CA9TYMS | |
| SCHEMBL8728048 | 0.86 | CA1 (0.40) | CA2CA1CA12CA9TAS1R3 | |
| SCHEMBL8726522 | 0.83 | CA2 (0.46) | CA2CA1CA12CA9TYMS | |
| SCHEMBL8724180 | 0.82 | CA2 (0.45) | CA2CA1CA12CA9TYMS | |
| SCHEMBL8726202 | 0.81 | CA2 (0.46) | CA2CA1CA12CA9TYMS | |
| SCHEMBL8722076 | 0.81 | CA2 (0.41) | CA2CA1CA12CA9TYMS | |
| SCHEMBL8724224 | 0.80 | CA2 (0.46) | CA2CA1CA12CA9TYMS | |
| SCHEMBL8726160 | 0.79 | MAPT (0.36) | CA1CA12CA9TAS1R3TAS1R1 | |
| SCHEMBL8722941 | 0.79 | CA2 (0.41) | CA2CA1CA12CA9TYMS | |
| SCHEMBL8722628 | 0.78 | MMP2 (0.37) | CA2CA1CA12CA9TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |