Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 7/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725881 | 0.91 | TYMS (0.45) | TYMSKDRTAS1R3TAS1R1MAPK14 | |
| SCHEMBL8722810 | 0.87 | TYMS (0.36) | TYMSKDRTAS1R3TAS1R1MAPK14 | |
| SCHEMBL9751830 | 0.84 | EGFR (0.45) | P2RY12 | |
| SCHEMBL8722824 | 0.84 | TYMS (0.37) | TYMS | |
| SCHEMBL6886320 | 0.81 | HDAC1 (0.44) | KDRTAS1R3TAS1R1MAPK14 | |
| SCHEMBL6886329 | 0.81 | HDAC1 (0.44) | KDRTAS1R3TAS1R1MAPK14 | |
| SCHEMBL28905229 | 0.78 | TYMS (0.53) | TYMS | |
| SCHEMBL2638767 | 0.78 | TYMS (0.53) | TYMS | |
| SCHEMBL6887186 | 0.78 | CLPP (0.43) | KDRTAS1R3TAS1R1MAPK14 | |
| SCHEMBL6887180 | 0.78 | CLPP (0.43) | KDRTAS1R3TAS1R1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696270-B1 | 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 1998-11-04 | — | — | EP | disclosed |