Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 3/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906473 | 0.85 | KMT2A (0.52) | LMNAHDAC6 | |
| SCHEMBL9751797 | 0.85 | P2RY12 (0.38) | DHFRP2RY12 | |
| SCHEMBL8722824 | 0.85 | TYMS (0.37) | LMNA | |
| SCHEMBL8722803 | 0.84 | TYMS (0.38) | P2RY12 | |
| SCHEMBL9087240 | 0.81 | P2RY12 (0.42) | P2RY12 | |
| SCHEMBL9087244 | 0.81 | P2RY12 (0.42) | P2RY12 | |
| SCHEMBL2244069 | 0.81 | ALDH1A1 (0.46) | LMNAP2RY12 | |
| SCHEMBL9556410 | 0.81 | P2RY12 (0.42) | P2RY12 | |
| SCHEMBL12356372 | 0.81 | ALDH1A1 (0.46) | LMNAP2RY12 | |
| SCHEMBL8722966 | 0.81 | ADAMTS5 (0.37) | DHFRP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433360-A1 | IMPROVEMENTS RELATING TO THE PRODUCTION OF PRODRUGS. | CANCER RES CAMPAIGN TECH (GB) | 1991-06-26 | — | — | EP | disclosed |
| WO-1990002729-A1 | IMPROVEMENTS RELATING TO THE PRODUCTION OF PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1990-03-22 | — | — | WO | disclosed |