Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 7/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725881 | 0.87 | TYMS (0.45) | TYMSMAPK14KDRP2RY12TAS1R3 | |
| SCHEMBL8722803 | 0.87 | TYMS (0.38) | TYMSMAPK14KDRP2RY12TAS1R3 | |
| SCHEMBL9751797 | 0.86 | P2RY12 (0.38) | P2RY12 | |
| SCHEMBL8723947 | 0.85 | TYMS (0.35) | TYMSP2RY12 | |
| SCHEMBL2638361 | 0.82 | TYMS (0.51) | TYMSMAPK14 | |
| SCHEMBL8726314 | 0.80 | CA2 (0.49) | TYMS | |
| SCHEMBL2638442 | 0.78 | TYMS (0.48) | TYMS | |
| SCHEMBL6886320 | 0.77 | HDAC1 (0.44) | MAPK14KDRPTPRCTAS1R3TAS1R1 | |
| SCHEMBL6886329 | 0.77 | HDAC1 (0.44) | MAPK14KDRPTPRCTAS1R3TAS1R1 | |
| SCHEMBL8726218 | 0.77 | CA2 (0.48) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696270-B1 | 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 1998-11-04 | — | — | EP | disclosed |