Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.38 |
| ▸ | DHFR | P00374 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906466 | 0.87 | ABCB1 (0.32) | P2RY12CA2CA1CA12CA9 | |
| SCHEMBL8723947 | 0.86 | TYMS (0.35) | P2RY12 | |
| SCHEMBL8722810 | 0.86 | TYMS (0.36) | P2RY12 | |
| SCHEMBL9751830 | 0.85 | EGFR (0.45) | P2RY12DHFR | |
| SCHEMBL8509781 | 0.83 | LMNA (0.33) | CA2CA1CA12CA9 | |
| SCHEMBL8726214 | 0.80 | CA2 (0.56) | DHFRCA2CA1CA12CA9 | |
| SCHEMBL2244069 | 0.77 | ALDH1A1 (0.46) | P2RY12CA12 | |
| SCHEMBL9556410 | 0.77 | P2RY12 (0.42) | P2RY12CA2 | |
| SCHEMBL12356372 | 0.77 | ALDH1A1 (0.46) | P2RY12CA12 | |
| SCHEMBL9087240 | 0.77 | P2RY12 (0.42) | P2RY12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433360-A1 | IMPROVEMENTS RELATING TO THE PRODUCTION OF PRODRUGS. | CANCER RES CAMPAIGN TECH (GB) | 1991-06-26 | — | — | EP | disclosed |
| WO-1990002729-A1 | IMPROVEMENTS RELATING TO THE PRODUCTION OF PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1990-03-22 | — | — | WO | disclosed |