SCHEMBL18302010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17998719	0.84	ALDH1A1 (0.59)	ALDH1A1HPRT1DNMT1CTSBS100A4
	SCHEMBL31219526	0.84	ALDH1A1 (0.59)	ALDH1A1HPRT1DNMT1CTSBS100A4
	SCHEMBL20029707	0.81	ALDH1A1 (0.51)	ALDH1A1HPRT1DNMT1CTSBS100A4
	SCHEMBL23499978	0.80	ALDH1A1 (0.50)	ALDH1A1HPRT1DNMT1CTSBS100A4
	SCHEMBL8722948	0.78	TDP1 (0.61)	ALDH1A1HPRT1CTSBTSHRTDP1
	SCHEMBL18302088	0.78	TSHR (0.54)	ALDH1A1HPRT1DNMT1CTSBS100A4
	SCHEMBL19660346	0.78	HPRT1 (0.61)	ALDH1A1HPRT1CTSBS100A4TSHR
	SCHEMBL24326903	0.78	ALDH1A1 (0.51)	ALDH1A1HPRT1DNMT1CTSBS100A4
	SCHEMBL8944624	0.77	MAPT (0.53)	ALDH1A1HPRT1CTSBS100A4TSHR
	SCHEMBL27009697	0.77	ALDH1A1 (0.59)	ALDH1A1HPRT1CTSBS100A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.