Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246386 | 0.93 | CA1 (0.42) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL4246389 | 0.93 | CA1 (0.42) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL28898391 | 0.93 | CA1 (0.42) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL4327761 | 0.81 | CA1 (0.40) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL6387799 | 0.79 | CA1 (0.39) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL27450052 | 0.78 | CA2 (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL30699980 | 0.78 | CA2 (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL29396741 | 0.76 | APLNR (0.46) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL7886691 | 0.76 | PRMT3 (0.39) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL7403322 | 0.75 | CA12 (0.36) | CA1CA2CA7CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801655-B1 | BASIC PROLINE-AMIDE DERIVATIVES OF GE 2270 AND GE 2270-LIKE ANTIBIOTICS | BIOSEARCH ITALIA SPA (IT) | 1998-04-15 | — | — | EP | disclosed |