Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246389 | 1.00 | CA1 (0.42) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL28898391 | 1.00 | CA1 (0.42) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL8723187 | 0.93 | CA1 (0.38) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL4327761 | 0.87 | CA1 (0.40) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL6387799 | 0.85 | CA1 (0.39) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL27450052 | 0.84 | CA2 (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL30699980 | 0.84 | CA2 (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL7886691 | 0.82 | PRMT3 (0.39) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL29396741 | 0.82 | APLNR (0.46) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL7403322 | 0.81 | CA12 (0.36) | CA1CA2CA7CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111646949-B | Preparation method of 2, 6-dimethylpiperazine dihydrochloride | 上海馨远医药科技有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-111646949-A | Preparation method of 2, 6-dimethylpiperazine dihydrochloride | 上海馨远医药科技有限公司 | 2020-09-11 | — | — | CN | claimed |
| CN-115551839-B | Heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-115003663-B | Novel heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2024-04-30 | — | — | CN | disclosed |
| US-20230148601-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230065953-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-03-02 | — | — | US | disclosed |
| US-20230058623-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| CN-115551839-A | Heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2022-12-30 | — | — | CN | disclosed |
| EP-4107151-A1 | HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2022-12-28 | — | — | EP | disclosed |
| EP-4065577-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2022-10-05 | — | — | EP | disclosed |
| EP-4061806-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2022-09-28 | — | — | EP | disclosed |
| US-7470795-B2 | Synthesis of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| EP-1979309-A2 | PROCESS FOR THE PREPARATION OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES AND INTERMEDIATES USED THEREIN | Boehringer Ingelheim International GmbH (DE) | 2008-10-15 | — | — | EP | disclosed |
| CN-101027304-A | Synthesis of 6, 7-dihydro-5H-imidazo [1, 2-A ] imidazole-3-sulfonamides | BOEHRINGER INGELHEIM INT (DE) | 2007-08-29 | — | — | CN | disclosed |
| WO-2007084882-A2 | PROCESS FOR THE PREPARATION OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES AND INTERMEDIATES USED THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-26 | — | — | WO | disclosed |
| US-20070173517-A1 | Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides | WIRTH THOMAS | 2007-07-26 | — | — | US | disclosed |
| EP-1776367-A1 | SYNTHESIS OF 6,7-DIHYDRO-5H-IMIDAZOÝ1,2-A¨IMIDAZOLE-3-SULFONIC ACID AMIDES | Boehringer Ingelheim International GmbH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006014828-A1 | SYNTHESIS OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3-SULFONIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |
| US-20060025447-A1 | Synthesis of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-02-02 | — | — | US | disclosed |
| CN-1308608-A | Substituted beta-amino acid inhibitors of methionine aminopeptidase-2 | ABBOTT LAB (US) | 2001-08-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065953-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | GLRX3, TARS2, CYP4F3 | CA1 4533/4885CA2 3818/4885CA7 4571/4885 |
| US-20070173517-A1 | Synthesis of 6,7-Dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides | ICAM1, CD14, VCAM1 | CA1 2571/4885CA2 2683/4885CA7 1614/4885 |
| US-20060025447-A1 | Synthesis of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid amides | ICAM1, CD14, VCAM1 | CA1 2267/4885CA2 2613/4885CA7 1487/4885 |
| US-20230148601-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | PRXL2A, GLRX3, CYP4F3 | CA1 4409/4885CA2 3584/4885CA7 4537/4885 |
| US-20230058623-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | PRXL2A, GLRX3, CYP4F3 | CA1 4409/4885CA2 3584/4885CA7 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.