Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619532 | 0.96 | SIGMAR1 (0.44) | SIGMAR1TSHRKCNH2DRD3CHRM1 | |
| SCHEMBL10733880 | 0.94 | SIGMAR1 (0.43) | SIGMAR1TSHRKCNH2DRD3CHRM1 | |
| SCHEMBL2879292 | 0.92 | KCNH2 (0.47) | SIGMAR1TSHRKCNH2DRD3CHRM1 | |
| SCHEMBL1068540 | 0.88 | CYP3A4 (0.39) | TSHRKCNH2DRD3CHRM1DRD1 | |
| SCHEMBL5039661 | 0.86 | HTR1A (0.42) | SIGMAR1DRD3DRD1OPRM1HTR1A | |
| SCHEMBL18213635 | 0.86 | HTR1A (0.42) | SIGMAR1DRD3DRD1OPRM1HTR1A | |
| SCHEMBL8773594 | 0.85 | SIGMAR1 (0.50) | SIGMAR1KCNH2DRD3CHRM1DRD1 | |
| SCHEMBL5033519 | 0.83 | MEN1 (0.45) | KCNH2DRD3CHRM1DRD1SLC6A2 | |
| SCHEMBL11814633 | 0.80 | SIGMAR1 (0.44) | SIGMAR1TSHRKCNH2DRD3CHRM1 | |
| SCHEMBL19753210 | 0.79 | KDM4E (0.40) | SIGMAR1KCNH2DRD3CHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789138-A | Optical recording medium and method of producing the same | RICOH COMPANY, LTD. (JP) | 1998-08-04 | — | — | US | disclosed |