Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619532 | 0.96 | SIGMAR1 (0.44) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10733880 | 0.94 | SIGMAR1 (0.43) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL8723759 | 0.92 | SIGMAR1 (0.42) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL1068540 | 0.87 | CYP3A4 (0.39) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL5039661 | 0.86 | HTR1A (0.42) | HTR1ADRD1OPRM1DRD3SIGMAR1 | |
| SCHEMBL18213635 | 0.86 | HTR1A (0.42) | HTR1ADRD1OPRM1DRD3SIGMAR1 | |
| SCHEMBL8773594 | 0.84 | SIGMAR1 (0.50) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL5033519 | 0.82 | MEN1 (0.45) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11814633 | 0.79 | SIGMAR1 (0.44) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL5003760 | 0.78 | KCNH2 (0.41) | KCNH2CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | claimed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | claimed |
| EP-1307239-A4 | RADIOPHARMACEUTICAL FOR DIAGNOSTIC IMAGING CONTAINING A TECHNETIUM-99M NITRIDE HETEROCOMPLEX | NIHON MEDIPHYSICS CO LTD (JP) | 2005-01-26 | — | — | EP | claimed |
| US-20040018147-A1 | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2004-01-29 | — | — | US | claimed |
| EP-1307239-A1 | RADIOPHARMACEUTICAL FOR DIAGNOSTIC IMAGING CONTAINING A TECHNETIUM-99M NITRIDE HETEROCOMPLEX | Nihon Medi-Physics Co., Ltd. (JP) | 2003-05-07 | — | — | EP | claimed |
| EP-0949265-B1 | RADIOACTIVE TRANSITION METAL NITRIDE HETERO-COMPLEX | NIHON MEDIPHYSICS CO LTD (JP) | 2003-05-07 | — | — | EP | claimed |
| US-20020048549-A1 | Radioactive transition metal nitride heterocomplex | DUATTI ADRIANO (IT) | 2002-04-25 | — | — | US | claimed |
| WO-2002009771-A1 | RADIOPHARMACEUTICAL FOR DIAGNOSTIC IMAGING CONTAINING A TECHNETIUM-99M NITRIDE HETEROCOMPLEX | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2002-02-07 | — | — | WO | claimed |
| US-6270745-B1 | FROM A BIS(PHOSPHINOALKYL) SULFIDE OR AMINE | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2001-08-07 | — | — | US | claimed |
| EP-0949265-A1 | RADIOACTIVE TRANSITION METAL NITRIDE HETERO-COMPLEX | Nihon Medi-Physics Co., Ltd. (JP) | 1999-10-13 | — | — | EP | claimed |
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
| US-7445765-B2 | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2008-11-04 | — | — | US | disclosed |
| EP-1307239-A4 | RADIOPHARMACEUTICAL FOR DIAGNOSTIC IMAGING CONTAINING A TECHNETIUM-99M NITRIDE HETEROCOMPLEX | NIHON MEDIPHYSICS CO LTD (JP) | 2005-01-26 | — | — | EP | disclosed |
| US-20040018147-A1 | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2004-01-29 | — | — | US | disclosed |
| US-4266085-A | Olefin disproportionation process | SHELL OIL COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4179402-A | Resin-metal-ligand composition | SHELL OIL COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4179403-A | Resin-ligand-metal complex compositions | SHELL OIL COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| EP-0005569-A1 | Resin-ligand-transition metal complex composition and processes for using this composition as catalyst | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-11-28 | — | — | EP | disclosed |
| EP-0002557-A2 | Resin-ligand transition metal complex composition and processes for using this composition as catalyst | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020048549-A1 | Radioactive transition metal nitride heterocomplex | SHBG, GNRHR, PRMT5 | KCNH2 4244/4885CHRM2 2907/4885HTR1A 2317/4885 |
| US-20040018147-A1 | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex | SHBG, TNNT2, TNNI3 | KCNH2 4196/4885CHRM2 3280/4885HTR1A 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.