Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723856 | 0.85 | HTR1D (0.50) | HRH3HTR1DHTR1AHTR1BHTR1F | |
| SCHEMBL8725928 | 0.85 | RORC (0.47) | MAPTHRH3HTR1DHTR1AHTR1B | |
| SCHEMBL8723596 | 0.84 | ALDH1A1 (0.44) | MAPTCYP3A4CYP2D6CYP2C19LMNA | |
| SCHEMBL30908934 | 0.84 | ALDH1A1 (0.44) | MAPTCYP3A4CYP2D6CYP2C19LMNA | |
| SCHEMBL8724094 | 0.84 | ACKR3 (0.39) | HRH3HTR1DHTR1AHTR1BHTR1F | |
| SCHEMBL8720774 | 0.83 | L3MBTL3 (0.43) | HRH3HTR1DHTR1AHTR1BHTR1F | |
| SCHEMBL8721836 | 0.82 | TMIGD3 (0.41) | HRH3HTR1DHTR1AHTR1BHTR1F | |
| Fumaric Acid SCHEMBL8725912 | 0.81 | HTR1D (0.46) | MAPTHRH3HTR1DHTR1AHTR1B | |
| Fumaric Acid SCHEMBL8725918 | 0.81 | HTR1D (0.46) | MAPTHRH3HTR1DHTR1AHTR1B | |
| SCHEMBL8720776 | 0.81 | HRH3 (0.47) | MAPTHRH3HTR1DHTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |