Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.33 |
| ▸ | CA9 | Q16790 | 6/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574176 | 0.79 | TSHR (0.56) | F2TMPRSS4CYP2D6TP53CYP1A2 | |
| SCHEMBL21377607 | 0.76 | F2 (0.42) | F2TMPRSS4CYP2D6TP53CYP1A2 | |
| SCHEMBL8724038 | 0.76 | F2 (0.42) | F2TMPRSS4CYP2D6TP53CYP1A2 | |
| SCHEMBL8328140 | 0.76 | ENPP2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL5664827 | 0.76 | POLB (0.57) | CYP2D6TSHRCA2CA9CA12 | |
| SCHEMBL8727720 | 0.74 | CA2 (0.41) | CA2CA9CA12POLBCA1 | |
| SCHEMBL10348147 | 0.73 | CYP3A4 (0.48) | F2TMPRSS4CYP2D6TP53CYP1A2 | |
| SCHEMBL20213950 | 0.73 | F2 (0.39) | F2TMPRSS4CYP2D6TP53CYP1A2 | |
| SCHEMBL11811491 | 0.73 | CYP2D6 (0.64) | F2TMPRSS4CYP2D6TP53CYP1A2 | |
| SCHEMBL11811487 | 0.73 | CYP2D6 (0.64) | F2TMPRSS4CYP2D6TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | claimed |