SCHEMBL10348147

SCHEMBL10348147

O=C=Nc1ccc(S(=O)(=O)F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.48
TSHR P16473 2/20 0.48
CA2 P00918 4/20 0.42
CA1 P00915 2/20 0.42
TDP1 Q9NUW8 3/20 0.41
MAPK1 P28482 1/20 0.41
F2 P00734 2/20 0.39
TMPRSS4 Q9NRS4 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
TP53 P04637 1/20 0.39
TRPA1 O75762 1/20 0.38
EPHX2 P34913 1/20 0.36
KDM4E B2RXH2 2/20 0.32
USP2 O75604 2/20 0.32
ALDH1A1 P00352 2/20 0.32
LTA P01374 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
P2RX3 P56373 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7180551 0.82 CYP3A4 (0.52) CYP3A4TSHRCA2CA1TDP1
SCHEMBL278353 0.82 CYP3A4 (0.52) CYP3A4TSHRCA2CA1TDP1
SCHEMBL6196292 0.81 CA1 (0.66) CYP3A4TSHRCA2CA1TDP1
SCHEMBL3044709 0.78 CYP3A4 (0.48) CYP3A4TSHRCA2CA1TDP1
SCHEMBL242025 0.78 CA2 (0.68) CYP3A4TSHRCA2CA1TDP1
SCHEMBL165024 0.78 CYP3A4 (0.48) CYP3A4TSHRCA2CA1TDP1
SCHEMBL2278953 0.78 POLB (0.53) CYP3A4TSHRCA2CA1TDP1
SCHEMBL31148855 0.78 CYP3A4 (0.48) CYP3A4TSHRCA2CA1TDP1
SCHEMBL15430 0.78 CYP3A4 (0.70) CYP3A4TSHRCA2CA1TDP1
SCHEMBL10535760 0.78 CYP3A4 (0.44) CYP3A4TSHRCA2CA1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2025-08-19 US disclosed
EP-4303981-A1 SECONDARY BATTERY AND BATTERY MODULE, BATTERY PACK AND ELECTRIC DEVICE THEREOF Contemporary Amperex Technology Co., Limited (CN) 2024-01-10 EP disclosed
EP-4295841-A2 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION The Scripps Research Institute (US) 2023-12-27 EP disclosed
US-20230387463-A1 SECONDARY BATTERY AND BATTERY MODULE, BATTERY PACK, AND ELECTRIC APPARATUS INCLUDING SAME CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2023-11-30 US disclosed
US-20230387463-A1 SECONDARY BATTERY AND BATTERY MODULE, BATTERY PACK, AND ELECTRIC APPARATUS INCLUDING SAME CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2023-11-30 US disclosed
US-20230387463-A1 SECONDARY BATTERY AND BATTERY MODULE, BATTERY PACK, AND ELECTRIC APPARATUS INCLUDING SAME CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2023-11-30 US disclosed
WO-2023220863-A1 SECONDARY BATTERY AND BATTERY MODULE, BATTERY PACK AND ELECTRIC DEVICE THEREOF 宁德时代新能源科技股份有限公司 2023-11-23 WO disclosed
EP-3892610-B1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION SCRIPPS RESEARCH INST (US) 2023-08-16 EP disclosed
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-10-06 US disclosed
US-20220000799-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-01-06 US disclosed
US-10117840-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2018-11-06 US disclosed
US-20170196985-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE 2017-07-13 US disclosed
EP-3151817-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF The Scripps Research Institute (US) 2017-04-12 EP disclosed
WO-2015188060-A1 FLUOROSULFONYL sEH INHIBITORS THE SCRIPPS RESEARCH INSTITUTE (US) 2015-12-10 WO disclosed
WO-2015188120-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2015-12-10 WO disclosed
WO-2015188060-A1 FLUOROSULFONYL sEH INHIBITORS THE SCRIPPS RESEARCH INSTITUTE (US) 2015-12-10 WO disclosed
EP-0184057-B1 COLOUR-PHOTOGRAPHIC MATERIAL CONTAINING A COUPLER Agfa-Gevaert AG (DE) 1990-04-11 EP disclosed
US-4617255-A PHENOLIC CYAN COUPLERS AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1986-10-14 US disclosed
EP-0184057-A2 Colour-photographic material containing a coupler Agfa-Gevaert AG (DE) 1986-06-11 EP disclosed
US-4438245-A FOR LIGHT SENSITIVE ELEMENTS FUJI PHOTO FILM CO., LTD. (JP) 1984-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170196985-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF CYP2F1, NAF1, CYP2S1 CYP3A4 42/4885TSHR 409/4885CA2 487/4885
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof GRB2, SCTR, OGFR CYP3A4 4138/4885TSHR 7/4885CA2 342/4885
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF QSOX1, YBX1, SFXN1 CYP3A4 3503/4885TSHR 397/4885CA2 577/4885
US-20220000799-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF PTMS, IGF2R, SCTR CYP3A4 4289/4885TSHR 17/4885CA2 564/4885
US-10117840-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof CYP2F1, NAF1, CYP2S1 CYP3A4 42/4885TSHR 409/4885CA2 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.