Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3643506 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTLMNACYP3A4 | |
| SCHEMBL3643243 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTLMNACYP3A4 | |
| SCHEMBL3716571 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTLMNACYP3A4 | |
| SCHEMBL5458574 | 0.79 | CA2 (0.53) | ALDH1A1SMN1; SMN2MAPTLMNACYP3A4 | |
| SCHEMBL8486571 | 0.77 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTLMNACYP3A4 | |
| SCHEMBL7895365 | 0.77 | MEN1 (0.54) | ALDH1A1SMN1; SMN2MAPTLMNAUSP30 | |
| SCHEMBL7802270 | 0.75 | FLT1 (0.54) | ALDH1A1SMN1; SMN2MAPTMAPK1TSHR | |
| SCHEMBL21540995 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTLMNACYP3A4 | |
| SCHEMBL7811320 | 0.75 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTLMNAUSP30 | |
| SCHEMBL8169641 | 0.75 | TMPRSS6 (0.55) | ALDH1A1SMN1; SMN2MAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011080-A1 | NOVEL 3,4-DIARYLOXAZOLONE DERIVATIVES, METHODS OF PREPARATION AND THERAPEUTIC USES THEREOF | LABORATOIRES UPSA (FR) | 1998-03-19 | — | — | WO | disclosed |