SCHEMBL8724310

SCHEMBL8724310

CC1(c2ccc(C(=O)OO)cc2)CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.38
RARB P10826 4/20 0.37
RARG P13631 4/20 0.37
RARA P10276 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
GAA P10253 1/20 0.36
LMNA P02545 3/20 0.36
ADORA3 P0DMS8 1/20 0.35
NPC1 O15118 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2C19 P33261 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8722942 0.98 SMN1; SMN2 (0.36) HSD11B1RARBRARGRARASMN1; SMN2
SCHEMBL14667564 0.86 CA1 (0.48) SMN1; SMN2LMNANPC1HTTRAB9A
SCHEMBL16377544 0.82 SMN1; SMN2 (0.53) SMN1; SMN2NPSR1GAALMNANPC1
SCHEMBL611940 0.82 ALDH1A1 (0.41) RARBRARGRARALMNANPC1
SCHEMBL418997 0.80 RARB (0.50) RARBRARGRARASMN1; SMN2
Cyclopropane SCHEMBL18860160 0.79 KDM4E (0.42) SMN1; SMN2NPSR1LMNANPC1HTT
SCHEMBL29119959 0.79 ALDH1A1 (0.40) HSD11B1RARBRARGRARALMNA
SCHEMBL29119962 0.78 RXRA (0.49) RARBRARGRARASMN1; SMN2
SCHEMBL10602015 0.77 ESR1 (0.42)
SCHEMBL29119934 0.77 ALDH1A1 (0.41) RARBRARGRARASMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5808114-A EPOXIDATION; REMOVING AROMATIC CARBOXYLIC ACID; CATALYTIC HYDROGENATION TO ALDEHYDE; OXIDATION; CIRCULATION; REUSE; FREE OF HYDROGEN PEROXIDE BASF AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
EP-0811003-B1 PROCESS FOR PRODUCING EPOXIDES USING AROMATIC PEROXYCARBOXYLIC ACIDS BASF AG (DE) 1998-09-02 EP disclosed
CN-1175949-A Process for producing eposides using aromatic peroxycarboxylic acids BASF AG (DE) 1998-03-11 CN disclosed