Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469211 | 0.87 | ENPP2 (0.40) | ENPP2HTR2CMEN1KMT2AORAI1 | |
| SCHEMBL3784784 | 0.87 | ENPP2 (0.40) | ENPP2HTR2CMEN1KMT2AORAI1 | |
| SCHEMBL3787321 | 0.80 | PTGDR2 (0.40) | ENPP2HTR2CMEN1KMT2AOPRM1 | |
| SCHEMBL29567858 | 0.80 | ENPP2 (0.38) | ENPP2HTR2CMEN1KMT2A | |
| SCHEMBL3783738 | 0.80 | ENPP2 (0.38) | ENPP2HTR2CMEN1KMT2A | |
| SCHEMBL17061132 | 0.78 | PTGDR2 (0.42) | ENPP2HTR2CMEN1KMT2AOPRM1 | |
| SCHEMBL2652565 | 0.78 | PTGDR2 (0.42) | ENPP2HTR2CMEN1KMT2AOPRM1 | |
| SCHEMBL31092302 | 0.75 | HTR2C (0.59) | HTR2C | |
| SCHEMBL22249252 | 0.75 | NOS3 (0.33) | ENPP2HTR2CMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27043164 | 0.74 | HTR2C (0.61) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853613-A | Chiral cyclohexyl compounds | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1998-12-29 | — | — | US | disclosed |