Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17061132 | 1.00 | PTGDR2 (0.42) | PTGDR2PTGS2MEN1KMT2AENPP2 | |
| SCHEMBL3787321 | 0.98 | PTGDR2 (0.40) | PTGDR2PTGS2MEN1KMT2AENPP2 | |
| SCHEMBL29567858 | 0.94 | ENPP2 (0.38) | PTGDR2PTGS2MEN1KMT2AENPP2 | |
| SCHEMBL3783738 | 0.94 | ENPP2 (0.38) | PTGDR2PTGS2MEN1KMT2AENPP2 | |
| SCHEMBL3784784 | 0.90 | ENPP2 (0.40) | MEN1KMT2AENPP2HTR2CSLC6A4 | |
| SCHEMBL29469211 | 0.90 | ENPP2 (0.40) | MEN1KMT2AENPP2HTR2CSLC6A4 | |
| SCHEMBL22249252 | 0.84 | NOS3 (0.33) | PTGDR2PTGS2MEN1KMT2AENPP2 | |
| SCHEMBL3789806 | 0.83 | ABCB1 (0.39) | PTGDR2PTGS2MEN1KMT2AHTR1A | |
| SCHEMBL28591184 | 0.83 | PTGS2 (0.45) | PTGDR2PTGS2MEN1KMT2A | |
| SCHEMBL30002535 | 0.83 | ABCB1 (0.39) | PTGDR2PTGS2MEN1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109021022-B | Luminescent diazabenzimidazole carbene metal complexes | UDC 爱尔兰有限责任公司 | 2021-04-16 | — | — | CN | disclosed |
| US-20170331054-A1 | LUMINESCENT DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES | UDC IRELAND LTD (IE) | 2017-11-16 | — | — | US | disclosed |
| US-20170331054-A1 | LUMINESCENT DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES | UDC IRELAND LTD (IE) | 2017-11-16 | — | — | US | disclosed |
| US-20170331054-A1 | LUMINESCENT DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES | UDC IRELAND LTD (IE) | 2017-11-16 | — | — | US | disclosed |
| EP-3239161-A1 | LUMINESCENT DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES | UDC Ireland Limited (IE) | 2017-11-01 | — | — | EP | disclosed |
| EP-3239161-A1 | LUMINESCENT DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES | UDC Ireland Limited (IE) | 2017-11-01 | — | — | EP | disclosed |
| EP-3027629-B1 | LUMINESCENT DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES | UDC IRELAND LTD (IE) | 2017-06-14 | — | — | EP | disclosed |
| EP-3027629-B1 | LUMINESCENT DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES | UDC IRELAND LTD (IE) | 2017-06-14 | — | — | EP | disclosed |
| US-9673408-B2 | Luminescent diazabenzimidazole carbene metal complexes | UDC IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |
| US-9673408-B2 | Luminescent diazabenzimidazole carbene metal complexes | UDC IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |
| EP-1778632-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006086488-A2 | SUBSTITUTED THIOPHENE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| WO-2005123673-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| US-20050014816-A1 | Thiophene amino acid derivatives, process for preparing them and pharmaceutical compositions containing them | PFIZER INC | 2005-01-20 | — | — | US | disclosed |
| WO-2005003115-A1 | THIOPHENE AMINO ACID DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170331054-A1 | LUMINESCENT DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES | OCIAD1, OCIAD2, CACNA1D | PTGDR2 790/4885PTGS2 3479/4885MEN1 1291/4885 |
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | PTGDR2 735/4885PTGS2 405/4885MEN1 718/4885 |
| US-20050014816-A1 | Thiophene amino acid derivatives, process for preparing them and pharmaceutical compositions containing them | MMP12, MMP9, MMP13 | PTGDR2 783/4885PTGS2 421/4885MEN1 2395/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | PTGDR2 863/4885PTGS2 443/4885MEN1 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.