Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29567858 | 0.89 | ENPP2 (0.38) | PTGDR2HTR2CENPP2PTGS2MEN1 | |
| SCHEMBL3783738 | 0.89 | ENPP2 (0.38) | PTGDR2HTR2CENPP2PTGS2MEN1 | |
| SCHEMBL3787321 | 0.86 | PTGDR2 (0.40) | PTGDR2HTR2CENPP2PTGS2MEN1 | |
| SCHEMBL17061132 | 0.84 | PTGDR2 (0.42) | NOS1PTGDR2HTR2CENPP2PTGS2 | |
| SCHEMBL2652565 | 0.84 | PTGDR2 (0.42) | NOS1PTGDR2HTR2CENPP2PTGS2 | |
| SCHEMBL29469211 | 0.82 | ENPP2 (0.40) | HTR2CENPP2MEN1KMT2A | |
| SCHEMBL3784784 | 0.82 | ENPP2 (0.40) | HTR2CENPP2MEN1KMT2A | |
| SCHEMBL8216158 | 0.77 | ALDH1A1 (0.34) | ENPP2MEN1KMT2A | |
| SCHEMBL3791444 | 0.76 | NOS3 (0.34) | NOS3NOS1NOS2HTR2C | |
| SCHEMBL8724934 | 0.75 | ENPP2 (0.40) | HTR2CENPP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11369295-B2 | Silicone hydrogel based fluorescent assay and contact lens | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2022-06-28 | — | — | US | disclosed |
| US-20200229740-A1 | Silicone Hydrogel Based Fluorescent Assay and Contact Lens | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11369295-B2 | Silicone hydrogel based fluorescent assay and contact lens | CD44, CRYAA, IGFBP1 | NOS3 2968/4885NOS1 2521/4885NOS2 2914/4885 |
| US-20200229740-A1 | Silicone Hydrogel Based Fluorescent Assay and Contact Lens | CD44, CRYAA, IGFBP1 | NOS3 2968/4885NOS1 2521/4885NOS2 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.