Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724957 | 0.90 | CHRNB2 (0.47) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL8727025 | 0.88 | MAPT (0.49) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL3977089 | 0.79 | CHRNB2 (0.64) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL8725786 | 0.79 | L3MBTL1 (0.53) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL8721558 | 0.79 | L3MBTL1 (0.53) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL8722487 | 0.79 | L3MBTL1 (0.53) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL14028449 | 0.78 | CHRNB2 (0.69) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL27634250 | 0.78 | CHRNB2 (0.59) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL8727019 | 0.77 | MAPT (0.50) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8724953 | 0.76 | LMNA (0.49) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800624-A | LIPOPHILIC POLYMER, HYDROPHOBIC PLASTICIZER, QUATERNARY AMMONIUM OR PHOSPHONIUM CARRIER | UNIVERSITY OF NOTRE DAME (US) | 1998-09-01 | — | — | US | disclosed |