Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727025 | 0.89 | MAPT (0.49) | MAPTDRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL8724957 | 0.87 | CHRNB2 (0.47) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8722484 | 0.81 | L3MBTL1 (0.54) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8721554 | 0.81 | L3MBTL1 (0.54) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8725784 | 0.81 | L3MBTL1 (0.54) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28181096 | 0.79 | DRD2 (0.74) | MAPTDRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL28180196 | 0.79 | DRD2 (0.74) | MAPTDRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL28180993 | 0.79 | DRD2 (0.74) | MAPTDRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL8724958 | 0.77 | CHRNB2 (0.46) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL28180985 | 0.77 | DRD2 (0.77) | MAPTDRD2DRD4DRD3CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800624-A | LIPOPHILIC POLYMER, HYDROPHOBIC PLASTICIZER, QUATERNARY AMMONIUM OR PHOSPHONIUM CARRIER | UNIVERSITY OF NOTRE DAME (US) | 1998-09-01 | — | — | US | disclosed |