Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13380458 | 0.86 | MAPT (0.54) | L3MBTL1GAANPC1RAB9AHSP90AA1 | |
| SCHEMBL22837858 | 0.85 | HSP90AA1 (0.40) | ADRB1L3MBTL1GAAHSP90AA1HSP90AB1 | |
| SCHEMBL5537556 | 0.85 | ME3 (0.52) | ACHEBACE1GAAHSP90AA1HSP90AB1 | |
| SCHEMBL8725144 | 0.85 | HSP90AA1 (0.40) | L3MBTL1GAAHSP90AA1HSP90AB1MAPT | |
| SCHEMBL5537549 | 0.85 | SMN1; SMN2 (0.42) | L3MBTL1GAANPC1RAB9AHSP90AA1 | |
| SCHEMBL13798544 | 0.84 | CHRNA7 (0.50) | ACHEBACE1L3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL5535481 | 0.83 | HSP90AA1 (0.41) | L3MBTL1GAAHSP90AA1HSP90AB1MAPT | |
| Benzene SCHEMBL27474247 | 0.82 | ME3 (0.57) | ACHEBACE1GAAHSP90AA1HSP90AB1 | |
| SCHEMBL8729299 | 0.82 | SMN1; SMN2 (0.40) | L3MBTL1GAANPC1RAB9AHSP90AA1 | |
| SCHEMBL803329 | 0.81 | ITGB3 (0.49) | HSP90AA1HSP90AB1AKT1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624584-B1 | Piperazine derivatives useful as calmodulin inhibitors | DAIICHI SEIYAKU CO (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5681954-A | HAS CALMODULIN INHIBITORY ACTIVITY; USEFUL IN TREATING DISEASES OF THE CIRCULATORY ORGANS OR IN CEREBRAL REGION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0624584-A1 | Piperazine derivatives useful as calmodolin inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-11-17 | — | — | EP | disclosed |