SCHEMBL872723

SCHEMBL872723

CCCN(CCC)c1cccc(C(=O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 2/20 0.49
KMT2A Q03164 1/20 0.49
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA6 P23280 1/20 0.44
CA9 Q16790 1/20 0.44
FOLH1 Q04609 1/20 0.43
LTB4R2 Q9NPC1 1/20 0.43
PPARA Q07869 1/20 0.43
PTPN1 P18031 1/20 0.42
RXRA P19793 1/20 0.42
KMO O15229 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28072408 0.90 ALDH1A1 (0.52) KMT2ALTB4R2KDM4EALDH1A1POLB
SCHEMBL11782996 0.87 L3MBTL1 (0.53) PTPN1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL872529 0.86 ALDH1A1 (0.56) HCAR3KMT2ACA12CA1CA2
SCHEMBL31412786 0.84 CYP2C19 (0.46) CA12CA1CA2CA6CA9
SCHEMBL31412787 0.84 CYP2C19 (0.46) CA12CA1CA2CA6CA9
SCHEMBL10689801 0.84 ALDH1A1 (0.47) HCAR3KMT2ALTB4R2KDM4EALDH1A1
SCHEMBL2808540 0.83 PTPN1 (0.46) CA12CA1CA2CA6CA9
SCHEMBL7470725 0.83 EGFR (0.51) KMT2ACA12CA1CA2CA6
SCHEMBL25024364 0.82 LOXL2 (0.50) KDM4EALDH1A1POLBHSD17B10
SCHEMBL4603912 0.81 APEX1 (0.42) HCAR3KMT2ALTB4R2PPARARXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10059900-B2 Aminobenzoic acid derivatives THE LUBRIZOL CORPORATION (US) 2018-08-28 US disclosed
US-20180002629-A1 AMINOBENZOIC ACID DERIVATIVES LUBRIZOL CORP (US) 2018-01-04 US disclosed
CN-103703114-B There is the lubricating composition improving tbn retention THE LUBRIZOL CORP. (US) 2016-02-10 CN disclosed
US-9222051-B2 Lubricating composition with improved TBN retention THE LUBRIZOL CORPORATION (US) 2015-12-29 US disclosed
CN-103210069-B Aminobenzoic acid derivatives THE LUBRIZOL CORP. (US) 2015-11-25 CN disclosed
US-20140187458-A1 Lubricating Composition With Improved TBN Retention THE LUBRIZOL CORPORATION (US) 2014-07-03 US disclosed
US-20130281336-A1 Aminobenzoic Acid Derivatives THE LUBRIZOL CORPORATION (US) 2013-10-24 US disclosed
EP-2619293-A1 AMINOBENZOIC ACID DERIVATIVES The Lubrizol Corporation (US) 2013-07-31 EP disclosed
CN-103210069-A Aminobenzoic acid derivatives LUBRIZOL CORP 2013-07-17 CN disclosed
WO-2012166781-A1 LUBRICATING COMPOSITION WITH IMPROVED TBN RETENTION THE LUBRIZOL CORPORATION (US) 2012-12-06 WO disclosed
WO-2012040021-A1 AMINOBENZOIC ACID DERIVATIVES THE LUBRIZOL CORPORATION (US) 2012-03-29 WO disclosed