SCHEMBL623741

SCHEMBL623741

c1cc2c(ccc3ccoc32)o1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.62
MAOB P27338 3/20 0.62
NFKB1 P19838 2/20 0.62
CYP1A1 P04798 3/20 0.41
CYP1B1 Q16678 3/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 3/20 0.36
KDM4E B2RXH2 3/20 0.36
CYP3A4 P08684 3/20 0.36
HSD17B10 Q99714 3/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
CCNT1 O60563 1/20 0.36
CDK7 P50613 1/20 0.36
CDK9 P50750 1/20 0.36
CCNH P51946 1/20 0.36
MNAT1 P51948 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29752613 1.00 MAOA (0.62) MAOAMAOBNFKB1CYP1A1CYP1B1
SCHEMBL19683556 0.89 MAOA (0.55) MAOAMAOBNFKB1CYP1A1CYP1B1
SCHEMBL19683358 0.85 MAOA (0.52) MAOAMAOBNFKB1CYP1A1CYP1B1
SCHEMBL16319037 0.79 MAOA (0.57) MAOAMAOBNFKB1CYP1A1CYP1B1
SCHEMBL12279132 0.77 MAOA (0.55) MAOAMAOBNFKB1CYP1A1CYP1B1
Angelicin SCHEMBL8726499 0.77 MAOA (1.00) MAOAMAOBNFKB1CYP1A1CYP1B1
Angelicin SCHEMBL376379 0.77 MAOA (1.00) MAOAMAOBNFKB1CYP1A1CYP1B1
Angelicin SCHEMBL29468230 0.77 MAOA (1.00) MAOAMAOBNFKB1CYP1A1CYP1B1
SCHEMBL4429415 0.76 PAX8 (0.48) MAOAMAOBNFKB1CYP1A1CYP1B1
SCHEMBL29591293 0.76 MAOA (0.46) MAOAMAOBNFKB1CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8617720-B2 Electroactive composition and electronic device made with the composition E I DU PONT DE NEMOURS AND COMPANY (US) 2013-12-31 US claimed
EP-2516583-A2 ELECTROACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E.I. Du Pont De Nemours And Company (US) 2012-10-31 EP claimed
US-20120187382-A1 ELECTRONIC DEVICES HAVING LONG LIFETIME E.I. DUPONT DE NEMOURS AND COMPANY (US) 2012-07-26 US claimed
EP-2379671-A2 ELECTRONIC DEVICES HAVING LONG LIFETIME E. I. du Pont de Nemours and Company (US) 2011-10-26 EP claimed
WO-2011087811-A2 ELECTROACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 WO claimed
US-20110147718-A1 ELECTROACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-06-23 US claimed
WO-2010075421-A2 ELECTRONIC DEVICES HAVING LONG LIFETIME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO claimed
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-20250186391-A1 ORAL COMPLEMENT FACTOR D INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-06-12 US disclosed
US-11957757-B2 Method for preparing stabilized metal ion ligand nanocomplex and compositions thereof AUBURN UNIVERSITY (US) 2024-04-16 US disclosed
CN-114195793-B Preparation method of chiral amino acid containing C-N-axis nitrogen aryl indole axis 南京工业大学 2023-05-23 CN disclosed
US-11539004-B2 Electroluminescent compound, thermally activated delayed fluorescence material, and application thereof WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2022-12-27 US disclosed
EP-4041238-A1 ORAL COMPLEMENT FACTOR D INHIBITORS Biocryst Pharmaceuticals, Inc. (US) 2022-08-17 EP disclosed
US-20120187383-A1 ELECTROACTIVE COMPOUND AND COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-07-26 US disclosed
WO-2012021315-A2 ELECTROACTIVE COMPOUND AND COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-02-16 WO disclosed
EP-2379671-A2 ELECTRONIC DEVICES HAVING LONG LIFETIME E. I. du Pont de Nemours and Company (US) 2011-10-26 EP disclosed
WO-2011087811-A2 ELECTROACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 WO disclosed
US-20110147718-A1 ELECTROACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-06-23 US disclosed
WO-2010075421-A2 ELECTRONIC DEVICES HAVING LONG LIFETIME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2006060082-A1 TRICYCLIC COMPOUNDS, PREPARATION THEREOF AND USE THEREOF AS CHOLINESTERASE ACTIVITY INHIBITORS THE GOVERNMENT OF THE U.S.A. as represented by THE SEC., DEPT. OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) 2006-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120187383-A1 ELECTROACTIVE COMPOUND AND COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION CCNL2, ESR1, ESR2 MAOA 1355/4885MAOB 1188/4885NFKB1 4292/4885
US-11957757-B2 Method for preparing stabilized metal ion ligand nanocomplex and compositions thereof NSFL1C, SOD1, CLTC MAOA 3686/4885MAOB 3889/4885NFKB1 565/4885
US-12558341-B2 Oral complement factor D inhibitors CFD, CFH, CFB MAOA 1416/4885MAOB 1035/4885NFKB1 829/4885
US-20250186391-A1 ORAL COMPLEMENT FACTOR D INHIBITORS CFD, CFH, CFB MAOA 795/4885MAOB 453/4885NFKB1 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.