⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721924 | 0.74 | — | — | |
| SCHEMBL8726821 | 0.66 | CTSS (0.31) | — | |
| SCHEMBL6414278 | 0.63 | ALDH1A1 (0.47) | — | |
| SCHEMBL9697740 | 0.61 | CTSS (0.52) | — | |
| SCHEMBL12092123 | 0.60 | — | — | |
| SCHEMBL4614441 | 0.59 | HPGD (0.40) | — | |
| SCHEMBL24745680 | 0.59 | CASP2 (0.47) | — | |
| SCHEMBL8738527 | 0.58 | — | — | |
| SCHEMBL26304773 | 0.58 | — | — | |
| SCHEMBL15099963 | 0.57 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813425-A4 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NEORX CORP (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5756685-A | MEDICAL DIAGNOSIS; THERAPY | NEORX CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0813425-A1 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NEORX CORPORATION (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5556982-A | Metal radionuclide labeled proteins for diagnosis and therapy | NEORX CORPORATION (US) | 1996-09-17 | — | — | US | disclosed |
| WO-1995002423-A1 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NEORX CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5242679-A | Complexes for imaging tumors | NEORX CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |
| US-5175343-A | For detection, radiotherapy and radeoimaging of tumors | NEORX CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5120526-A | Chelate compounds | NEORX CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0188256-B1 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NeoRx (US) | 1991-08-21 | — | — | EP | disclosed |
| US-5037630-A | Chelated polypeptides specific for tumors, improved imaging | NEORX CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| US-4897255-A | Metal radionuclide labeled proteins for diagnosis and therapy | NEORX CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |
| EP-0188256-A2 | Metal radionuclide labeled proteins for diagnosis and therapy | NeoRx (US) | 1986-07-23 | — | — | EP | disclosed |