Herbacetin

Herbacetin

SCHEMBL872691

O=c1c(O)c(-c2ccc(O)cc2)oc2c(O)c(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 1.00
MEN1 O00255 7/20 0.76
MAPT P10636 7/20 0.76
KMT2A Q03164 7/20 0.76
KDM4E B2RXH2 6/20 0.76
ALDH1A1 P00352 5/20 0.76
HPGD P15428 5/20 0.76
SLCO2B1 O94956 4/20 0.76
ALOX15 P16050 4/20 0.76
DAPK1 P53355 4/20 0.76
CYP19A1 P11511 4/20 0.76
APEX1 P27695 3/20 0.76
GLA P06280 1/20 0.76
HSPD1 P10809 1/20 0.76
RAD52 P43351 1/20 0.76
HSPE1 P61604 1/20 0.76
TST Q16762 1/20 0.76
BCL9 O00512 6/20 0.67
CTNNB1 P35222 6/20 0.67
ABCB1 P08183 6/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Herbacetin SCHEMBL31442430 1.00 FBP1 (1.00) FBP1MEN1MAPTKMT2AKDM4E
SCHEMBL16682485 0.88 FBP1 (0.78) FBP1MEN1MAPTKMT2AKDM4E
SCHEMBL26204956 0.88 FBP1 (0.78) FBP1MEN1MAPTKMT2AKDM4E
SCHEMBL6567404 0.87 FBP1 (0.76) FBP1MEN1MAPTKMT2AKDM4E
Gossypetin SCHEMBL29929428 0.86 MEN1 (1.00) FBP1MEN1MAPTKMT2AKDM4E
Gossypetin SCHEMBL157033 0.86 MEN1 (1.00) FBP1MEN1MAPTKMT2AKDM4E
Gossypetin SCHEMBL29419067 0.86 MEN1 (1.00) FBP1MEN1MAPTKMT2AKDM4E
SCHEMBL12640014 0.85 MEN1 (0.77) FBP1MEN1MAPTKMT2AKDM4E
SCHEMBL30190288 0.85 MEN1 (0.77) FBP1MEN1MAPTKMT2AKDM4E
Gossypetin SCHEMBL16782915 0.85 MEN1 (0.97) FBP1MEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743565-A2 CYTOKINE ENCODING LENTIVIRAL VECTORS AND USES THEREOF FOR MAKING TUMOR INFILTRATING LYMPHOCYTES Iovance Biotherapeutics, Inc. (US) 2026-05-20 EP claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
EP-4583889-A1 PROCESSES FOR GENERATING TIL PRODUCTS USING PD-1/TIGIT TALEN DOUBLE KNOCKDOWN Iovance Biotherapeutics, Inc. (US) 2025-07-16 EP claimed
WO-2025067472-A1 METHODS OF CULTURING GAMMA DELTA T CELLS NANJING LEGEND BIOTECH CO., LTD. (CN) 2025-04-03 WO claimed
WO-2025015318-A2 CYTOKINE ENCODING LENTIVIRAL VECTORS AND USES THEREOF FOR MAKING TUMOR INFILTRATING LYMPHOCYTES IOVANCE BIOTHERAPEUTICS, INC. (US) 2025-01-16 WO claimed
US-20250000903-A1 EXPANSION PROCESSES AND AGENTS FOR TUMOR INFILTRATING LYMPHOCYTES IOVANCE BIOTHERAPEUTICS, INC. 2025-01-02 US claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO claimed
US-20240368547-A1 TIL EXPANSION PROCESSES USING SPECIFIC CYTOKINE COMBINATIONS AND/OR AKTI TREATMENT IOVANCE BIOTHERAPEUTICS, INC. 2024-11-07 US claimed
EP-4404969-A1 EXPANSION PROCESSES AND AGENTS FOR TUMOR INFILTRATING LYMPHOCYTES Iovance Biotherapeutics, Inc. (US) 2024-07-31 EP claimed
US-20240191191-A1 METHODS FOR INFILTRATING LYMPHOCYTE (TIL) EXPANSION RELATED TO CD39/CD69 SELECTION AND GENE KNOCKOUT IN TILS IOVANCE BIOTHERAPEUTICS INC (US) 2024-06-13 US claimed
EP-3418274-A1 METHOD FOR EXTRACTING HERBACETIN FROM RHODIOLA ROSEA Taizhou Forever Biotechnology Co., Ltd. (CN) 2018-12-26 EP claimed
US-20180354926-A1 Method for Extracting Herbacetin from Plants of Rhodiola L. Taizhou Danding Biotechnology Co., Ltd. (CN) 2018-12-13 US claimed
US-20140303244-A1 METHODS OF TREATING CANCER WITH HERBACETIN NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2014-10-09 US claimed
WO-2013075120-A1 METHODS OF TREATING CANCER WITH HERBACETIN REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2013-05-23 WO claimed
CN-101879156-B Medicinal composition and application thereof SHANGHAI INST PHARM INDUSTRY 2013-01-30 CN claimed
CN-101879156-A Medicinal composition and application thereof SHANGHAI INST PHARM INDUSTRY 2010-11-10 CN claimed
WO-2009151173-A1 PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF VIRAL DISEASES CONTAINING RHODIOLA EXTRACTS, FRACTIONS, THE ISOLATED FLAVONOID COMPOUNDS THEREFROM, DERIVATIVES COMPOUNDS THEREOF OR THE PHARMACEUTICALLY ACCEPTABLE SALTS AS AN ACTIVE INGREDIENT KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2009-12-17 WO claimed
CN-101119719-A The use of flavonol and flavonol glycosides for stimulating growth of renal tubular epithelial cells to secrete the kidney secreting bone growth factor MIAN LONG (US) 2008-02-06 CN claimed
US-20080009451-A1 Applications of kidney secreted bone growth factor and pharmaceutical use of flavonol and flavonol glycosides for stimulating the secretion of kidney secreted bone growth factor LONG MIAN 2008-01-10 US claimed
EP-1847265-A1 THE USE OF FLAVONOL AND FLAVONOL GLYCOSIDES FOR STIMULATING GROWTH OF RENAL TUBULAR EPITHELIAL CELLS TO SECRETE THE KIDNEY SECRETING BONE GROWTH FACTOR Long, Mian (US) 2007-10-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368547-A1 TIL EXPANSION PROCESSES USING SPECIFIC CYTOKINE COMBINATIONS AND/OR AKTI TREATMENT IL15, IL15RA, ICOS FBP1 4326/4885MEN1 3114/4885MAPT 2664/4885
US-20140303244-A1 METHODS OF TREATING CANCER WITH HERBACETIN ALDOA, DERA, GAPDH FBP1 214/4885MEN1 1153/4885MAPT 2719/4885
US-20240191191-A1 METHODS FOR INFILTRATING LYMPHOCYTE (TIL) EXPANSION RELATED TO CD39/CD69 SELECTION AND GENE KNOCKOUT IN TILS CD69, CD209, ICOS FBP1 2076/4885MEN1 4832/4885MAPT 4516/4885
US-20250000903-A1 EXPANSION PROCESSES AND AGENTS FOR TUMOR INFILTRATING LYMPHOCYTES NFATC1, MKI67, ICOS FBP1 3808/4885MEN1 3972/4885MAPT 4585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.