Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254800 | 0.84 | MAPT (0.66) | MAPTRAB9ACA1CA2SMN1; SMN2 | |
| SCHEMBL1249230 | 0.84 | MAPT (0.66) | MAPTRAB9ACA1CA2SMN1; SMN2 | |
| SCHEMBL29723230 | 0.83 | MAPT (0.64) | MAPTRAB9ACA1CA2SMN1; SMN2 | |
| SCHEMBL1503512 | 0.83 | MAPT (0.64) | MAPTRAB9ACA1CA2SMN1; SMN2 | |
| SCHEMBL9353433 | 0.81 | L3MBTL1 (0.63) | MAPTRAB9ASMN1; SMN2LMNAGAA | |
| SCHEMBL11082868 | 0.81 | GABRA1 (0.46) | MAPTRAB9ACA1CA2SMN1; SMN2 | |
| SCHEMBL1951546 | 0.81 | MAPT (1.00) | MAPTRAB9ACA1CA2SMN1; SMN2 | |
| SCHEMBL8729249 | 0.80 | MRGPRX4 (0.53) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL8011558 | 0.79 | PKM (0.58) | RAB9ACA1CA2SMN1; SMN2NPC1 | |
| SCHEMBL10295156 | 0.79 | MAPT (0.75) | MAPTRAB9ACA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |