Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392025 | 0.88 | KMT2A (0.37) | HSD17B10KMT2AKDM4ETDP1TSHR | |
| SCHEMBL8390748 | 0.84 | ALDH1A1 (0.34) | HSD17B10KMT2AKDM4EL3MBTL1TSHR | |
| SCHEMBL8725793 | 0.79 | KMT2A (0.34) | HSD17B10KMT2AKDM4ETHRB | |
| SCHEMBL8391826 | 0.75 | ALDH1A1 (0.41) | HSD17B10KMT2AKDM4ETSHR | |
| Hexane SCHEMBL8729907 | 0.74 | ALDH1A1 (0.40) | HSD17B10KMT2AKDM4ETHRBTSHR | |
| SCHEMBL8724264 | 0.73 | MEN1 (0.32) | HSD17B10KMT2ATSHR | |
| SCHEMBL8307823 | 0.72 | ALDH1A1 (0.37) | HSD17B10KMT2AKDM4ETSHRHTT | |
| SCHEMBL8389796 | 0.72 | RAB9A (0.43) | HSD17B10KMT2APOLBTSHRHTT | |
| SCHEMBL8752728 | 0.72 | PDE2A (0.32) | — | |
| SCHEMBL27367265 | 0.72 | ALDH1A1 (0.47) | KMT2AKDM4ETDP1POLBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625508-B1 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-08-19 | — | — | EP | disclosed |
| EP-0625508-A2 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |