Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CBFB | Q13951 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10100473 | 0.88 | MEN1 (0.40) | ALDH1A1MAPTRAB9AMAPK1TDP1 | |
| SCHEMBL7480856 | 0.85 | SLC6A2 (0.45) | MAPTRAB9AHTTKMT2ALMNA | |
| SCHEMBL19555141 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPTRAB9AMAPK1TDP1 | |
| SCHEMBL11948155 | 0.78 | TDP1 (0.36) | ALDH1A1MAPTRAB9AMAPK1TDP1 | |
| SCHEMBL873778 | 0.78 | CASP3 (0.52) | ALDH1A1MAPTRAB9AMAPK1TDP1 | |
| SCHEMBL11342821 | 0.77 | HTT (0.63) | ALDH1A1MAPTRAB9AMAPK1TDP1 | |
| SCHEMBL11948097 | 0.76 | TDP1 (0.35) | ALDH1A1MAPTRAB9AMAPK1TDP1 | |
| SCHEMBL11948095 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTRAB9AL3MBTL1HPGD | |
| SCHEMBL31577784 | 0.76 | TAAR1 (0.46) | ALDH1A1RAB9AL3MBTL1ATMMEN1 | |
| SCHEMBL10100557 | 0.75 | MAOB (0.40) | ALDH1A1L3MBTL1MAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| CN-1067052-A | The diaminophthalimides and the analogue thereof that replace | CIBA GEIGY AG (CH) | 1992-12-16 | — | — | CN | disclosed |