Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727685 | 0.76 | ALDH1A1 (0.45) | ATMCA9RAB9AALDH1A1MEN1 | |
| SCHEMBL6825326 | 0.70 | TSHR (0.60) | TAAR1ATMTMEM97SIGMAR1CA1 | |
| SCHEMBL31577947 | 0.70 | SIGMAR1 (0.51) | SIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7480856 | 0.70 | SLC6A2 (0.45) | RAB9AKMT2ANPC1 | |
| SCHEMBL10156581 | 0.68 | TAAR1 (0.76) | TAAR1ATMTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL4418547 | 0.67 | CASP3 (0.59) | CA1CA2CA9RAB9AALDH1A1 | |
| SCHEMBL10100473 | 0.66 | MEN1 (0.40) | ATMRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL1878 | 0.66 | TAAR1 (1.00) | TAAR1ATMTMEM97SIGMAR1RAB9A | |
| SCHEMBL19355275 | 0.66 | TAAR1 (1.00) | TAAR1ATMTMEM97SIGMAR1RAB9A | |
| Phthalic Anhydride SCHEMBL29257249 | 0.66 | TMEM97 (0.66) | TAAR1ATMTMEM97SIGMAR1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163042-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163042-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | TAAR1 2050/4885ATM 194/4885TMEM97 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.