Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323569 | 0.74 | FDPS (0.55) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL27971734 | 0.72 | LMNA (0.48) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28916662 | 0.71 | APP (0.44) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL15525582 | 0.70 | APP (0.43) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL3181161 | 0.70 | APP (0.43) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL23927997 | 0.70 | APP (0.43) | APPLMNASLC6A6CYP2C19BLM | |
| Ethylenediamine SCHEMBL1487301 | 0.69 | APP (0.78) | APPLMNASLC6A6CYP2C19BLM | |
| Tramiprosate SCHEMBL26759 | 0.69 | — | — | |
| SCHEMBL3134538 | 0.69 | APP (0.46) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL3134376 | 0.69 | APP (0.46) | APPLMNASLC6A6CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733787-A | COPPER IONS, HYDROPEROXIDE, CHELATING AGENT | BAYER CORPORATION (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0814335-A2 | Method for the detection of creatinine | Bayer Corporation (US) | 1997-12-29 | — | — | EP | disclosed |