Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871578 | 0.78 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4013884 | 0.77 | SLC6A3 (0.60) | SLC6A3SLC6A4ESR1SLC6A2HDAC4 | |
| SCHEMBL872384 | 0.76 | SLC6A3 (0.50) | SLC6A3SLC6A4SLC6A2HTR2A | |
| SCHEMBL805452 | 0.74 | ESR1 (0.43) | SLC6A3SLC6A4ESR1SLC6A2HDAC4 | |
| SCHEMBL15042437 | 0.74 | ESR1 (0.41) | SLC6A3SLC6A4ESR1SLC6A2HDAC4 | |
| SCHEMBL15066212 | 0.73 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10180722 | 0.73 | SLC6A3 (0.41) | SLC6A3SLC6A4ESR1SLC6A2HDAC4 | |
| SCHEMBL8606048 | 0.72 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2HTR2AOPRK1 | |
| SCHEMBL871941 | 0.72 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2HTR2AOPRK1 | |
| SCHEMBL8040636 | 0.72 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2HTR2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003501-A2 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING CYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |