Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334905 | 0.89 | MIF (0.45) | MIF | |
| SCHEMBL1334903 | 0.72 | MIF (0.41) | MIFGRIN1GRIN2A | |
| SCHEMBL28593714 | 0.71 | GRIN1 (0.40) | GRIN1GRIN2A | |
| SCHEMBL8728324 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL30571084 | 0.66 | GRIN1 (0.41) | GRIN1GRIN2A | |
| SCHEMBL7061213 | 0.63 | MAOA (0.39) | MIFMAOB | |
| SCHEMBL4204090 | 0.63 | KCNH2 (0.65) | GRIN1GRIN2AKDM1AMAOB | |
| Isopropylbenzene SCHEMBL28259979 | 0.62 | TAAR1 (0.47) | GRIN1GRIN2A | |
| SCHEMBL9768636 | 0.61 | GRIN1 (0.70) | GRIN1GRIN2AKDM1AMAOB | |
| SCHEMBL28568357 | 0.60 | MTOR (0.69) | GRIN1GRIN2AKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714166-A | Bioactive and/or targeted dendrimer conjugates | THE DOW CHEMICAL COMPANY (US) | 1998-02-03 | — | — | US | disclosed |