Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 4/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712453 | 0.79 | ALOX5AP (0.36) | DGAT1KDM1AKDM1BNPC1TP53 | |
| SCHEMBL28599064 | 0.76 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1 | |
| SCHEMBL5360881 | 0.73 | HTT (0.37) | NPC1RAB9APYCR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17391090 | 0.73 | ADRA2B (0.36) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL8725010 | 0.73 | HTR2A (0.36) | AHRTP53 | |
| SCHEMBL19126026 | 0.71 | HSP90AA1 (0.41) | ALDH1A1LMNAAHR | |
| SCHEMBL14353891 | 0.70 | KDM1A (0.35) | KDM1AKDM1B | |
| SCHEMBL31277494 | 0.70 | KDM1A (0.33) | KDM1AKDM1B | |
| SCHEMBL31277447 | 0.69 | — | — | |
| SCHEMBL29388695 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440938-B1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC (US) | 2023-07-12 | — | — | EP | disclosed |
| CN-108689924-B | 4-amino-6- (4-substituted phenyl) -pyridine-2-carboxylic acid esters and their use as herbicides | 美国陶氏益农公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-2725903-B1 | 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-3440938-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2019-02-13 | — | — | EP | disclosed |
| EP-2967069-B1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND 6-AMINO-2-(4-SUBSTITUTED-PHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2018-10-24 | — | — | EP | disclosed |
| US-9518018-B2 | 3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2016-12-13 | — | — | US | disclosed |
| US-9518018-B2 | 3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2016-12-13 | — | — | US | disclosed |
| US-9518018-B2 | 3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2016-12-13 | — | — | US | disclosed |
| CN-103763923-B | 3-alkoxy-4-amino-6- (substituted) picolinates, 3-thioalkyl-4-amino-6- (substituted) picolinates, and 3-amino-4-amino-6- (substituted) picolinates and their use as herbicides | 陶氏益农公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-2967069-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND 6-AMINO-2-(4-SUBSTITUTED-PHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20140274696-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND 6-AMINO-2-(4-SUBSTITUTED-PHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-8754229-B2 | 3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-8754229-B2 | 3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-8754229-B2 | 3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-06-17 | — | — | US | disclosed |
| EP-2725903-A1 | 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2014-05-07 | — | — | EP | disclosed |
| WO-2013003740-A1 | 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-01-03 | — | — | WO | disclosed |
| US-20130005574-A1 | 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2013-01-03 | — | — | US | disclosed |
| US-20130005574-A1 | 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES | CORTEVA AGRISCIENCE LLC | 2013-01-03 | — | — | US | disclosed |
| US-5730901-A | Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0742222-A2 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005574-A1 | 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES | DDT, AADAC, AADAT | DGAT1 1436/4885KDM1A 2504/4885KDM1B 2109/4885 |
| US-20140274696-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND 6-AMINO-2-(4-SUBSTITUTED-PHENYL)-PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, P2RX6, ABAT | DGAT1 4474/4885KDM1A 2443/4885KDM1B 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.