Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728544 | 0.79 | DGAT1 (0.39) | ALOX5APFEN1DGAT1NPC1KDM1A | |
| SCHEMBL30075934 | 0.77 | PDE3B (0.39) | ALOX5APFEN1NMUR2DGAT1NPC1 | |
| SCHEMBL23723931 | 0.77 | PDE3B (0.39) | ALOX5APFEN1NMUR2DGAT1NPC1 | |
| SCHEMBL31310573 | 0.77 | DGAT1 (0.46) | ALOX5APFEN1NMUR2DGAT1NPC1 | |
| SCHEMBL14520998 | 0.77 | DGAT1 (0.46) | ALOX5APFEN1NMUR2DGAT1NPC1 | |
| SCHEMBL9926822 | 0.76 | PDE3B (0.39) | NPC1PDE3BPDE3A | |
| SCHEMBL30608294 | 0.72 | — | — | |
| SCHEMBL856445 | 0.72 | — | — | |
| SCHEMBL711925 | 0.70 | RARB (0.39) | NPC1HTTPDE3BPDE3AALOX5 | |
| SCHEMBL30075973 | 0.70 | CYP11B1 (0.37) | ALOX5APFEN1NMUR2DGAT1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350100-B2 | Process for the preparation of ring compounds | MERCK PATENT GMBH (DE) | 2013-01-08 | — | — | US | disclosed |
| US-8350100-B2 | Process for the preparation of ring compounds | MERCK PATENT GMBH (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20120149943-A1 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS | MERCK GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
| US-20120149943-A1 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS | MERCK GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
| US-8124817-B2 | Process for the preparation of ring compounds | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124817-B2 | Process for the preparation of ring compounds | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| EP-2332944-A2 | Process for the preparation of ring compounds | Merck Patent GmbH (DE) | 2011-06-15 | — | — | EP | disclosed |
| US-20110034738-A1 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS | PAULUTH DETLEF | 2011-02-10 | — | — | US | disclosed |
| US-20110034738-A1 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS | PAULUTH DETLEF | 2011-02-10 | — | — | US | disclosed |
| US-7842845-B2 | Process for the preparation of ring compounds | MERCK GMBH (DE) | 2010-11-30 | — | — | US | disclosed |
| EP-2103589-A1 | Polypenylenes as liquid crystals | Merck Patent GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| US-20080319235-A1 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS | PAULUTH DETLEF | 2008-12-25 | — | — | US | disclosed |
| US-20080319235-A1 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS | PAULUTH DETLEF | 2008-12-25 | — | — | US | disclosed |
| US-7411100-B2 | Process for the preparation of ring compounds | MERCK GMBH (DE) | 2008-08-12 | — | — | US | disclosed |
| US-7411100-B2 | Process for the preparation of ring compounds | MERCK GMBH (DE) | 2008-08-12 | — | — | US | disclosed |
| US-7183447-B2 | Process for the preparation of ring compounds | MERCK PATENT GMBH (DE) | 2007-02-27 | — | — | US | disclosed |
| US-7183447-B2 | Process for the preparation of ring compounds | MERCK PATENT GMBH (DE) | 2007-02-27 | — | — | US | disclosed |
| US-20060216754-A1 | Process for the preparation of ring compounds | PAULUTH DETLEF | 2006-09-28 | — | — | US | disclosed |
| US-20040006235-A1 | Process for the preparation of ring compounds | MERCK PATENT GMBH (DE) | 2004-01-08 | — | — | US | disclosed |
| EP-1346995-A1 | Process for the preparation of ring compounds | MERCK PATENT GmbH (DE) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006235-A1 | Process for the preparation of ring compounds | NBAS, HDHD5, DBF4 | ALOX5AP 3832/4885FEN1 2236/4885NMUR2 2685/4885 |
| US-20120149943-A1 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS | NBAS, HDHD5, DBF4 | ALOX5AP 3845/4885FEN1 2267/4885NMUR2 2677/4885 |
| US-20080319235-A1 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS | NBAS, HDHD5, DBF4 | ALOX5AP 3832/4885FEN1 2236/4885NMUR2 2685/4885 |
| US-20110034738-A1 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS | NBAS, HDHD5, DBF4 | ALOX5AP 3832/4885FEN1 2236/4885NMUR2 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.