Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901792 | 0.67 | LOXL2 (0.43) | IDO1HRH4 | |
| SCHEMBL6688749 | 0.65 | THRB (0.31) | DAOSMN1; SMN2ALDH1A1 | |
| SCHEMBL5757196 | 0.63 | KDM4E (0.44) | DAOKDM4EMAPTHPGDSRD5A2 | |
| SCHEMBL10783455 | 0.62 | L3MBTL1 (0.32) | — | |
| SCHEMBL9752038 | 0.62 | — | — | |
| SCHEMBL7890207 | 0.60 | KDM4E (0.72) | DAOKDM4EMAPTHPGDSRD5A2 | |
| SCHEMBL7890214 | 0.60 | KDM4E (0.72) | DAOKDM4EMAPTHPGDSRD5A2 | |
| Indole-2-Carboxylic Acid SCHEMBL1935 | 0.60 | KDM4E (1.00) | DAOKDM4EMAPTHPGDSRD5A2 | |
| Indole-2-Carboxylic Acid SCHEMBL29395165 | 0.60 | KDM4E (1.00) | DAOKDM4EMAPTHPGDSRD5A2 | |
| SCHEMBL21048591 | 0.59 | DAO (0.46) | DAOKDM4EMAPTHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736518-A | Peptide compounds of (L) amino acids and ring molecules, and therapeutical applications thereof | POLIFARMA S.P.A. (IT) | 1998-04-07 | — | — | US | disclosed |
| US-5504071-A | HYPOTENSIVE AGENTS | POLIFARMA S.P.A. (IT) | 1996-04-02 | — | — | US | disclosed |