Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728797 | 1.00 | TLR8 (0.35) | TLR8SMPD2 | |
| SCHEMBL1469843 | 0.75 | TLR8 (0.50) | TLR8SMPD2 | |
| SCHEMBL1469842 | 0.75 | TLR8 (0.50) | TLR8SMPD2 | |
| SCHEMBL8206128 | 0.71 | TLR8 (0.51) | TLR8 | |
| SCHEMBL8728515 | 0.69 | TLR8 (0.35) | TLR8 | |
| SCHEMBL8728518 | 0.69 | TLR8 (0.35) | TLR8 | |
| SCHEMBL5431024 | 0.69 | IAPP (0.46) | TLR8 | |
| SCHEMBL28015702 | 0.68 | PTGS2 (0.40) | TLR8 | |
| SCHEMBL1469922 | 0.68 | TLR8 (0.50) | TLR8SMPD2 | |
| SCHEMBL1469921 | 0.68 | TLR8 (0.50) | TLR8SMPD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |