Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL9621813 | 0.89 | LMNA (0.50) | LMNATDP1AKR1B1TSHR | |
| Glycerin SCHEMBL1579919 | 0.89 | LMNA (0.50) | LMNATDP1AKR1B1 | |
| Propylene Glycol SCHEMBL118981 | 0.89 | LMNA (0.67) | LMNATDP1TSHRTHRB | |
| Acetaldehyde SCHEMBL212729 | 0.86 | LMNA (0.71) | LMNATDP1TSHRTHRB | |
| Propylene Glycol SCHEMBL9721324 | 0.86 | LMNA (0.46) | LMNATDP1TSHR | |
| Propylene Glycol SCHEMBL1532415 | 0.84 | LMNA (0.55) | LMNATDP1TSHRTHRB | |
| Propylene Glycol SCHEMBL17219435 | 0.84 | LMNA (0.44) | LMNATDP1 | |
| 2-Methylbutanal SCHEMBL21434919 | 0.84 | LMNA (0.44) | LMNATDP1AKR1B1TSHR | |
| Propylene Glycol SCHEMBL10380801 | 0.82 | LMNA (0.57) | LMNATDP1TSHRTHRB | |
| Acetaldehyde SCHEMBL22361219 | 0.81 | LMNA (0.63) | LMNATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11806448-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2023-11-07 | — | — | US | claimed |
| CN-116103709-A | PCB through hole copper electroplating solution and preparation method thereof | 南通赛可特电子有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-115787053-A | High-stability electroplating additive and preparation method thereof | 南通赛可特电子有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-111449270-B | Smoke softener, electronic cigarette tobacco tar and preparation method thereof | 深圳瀚星翔科技有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-113667537-A | Fengxian golden yellow peach essence and preparation method thereof | 上海应用技术大学 | 2021-11-19 | — | — | CN | claimed |
| CN-111449270-A | Smoke softener, electronic cigarette tobacco tar and preparation method thereof | 深圳瀚星翔科技有限公司 | 2020-07-28 | — | — | CN | claimed |
| JP-1056798-A | — | — | None | — | — | JP | disclosed |
| US-20240016966-A1 | FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS | Arylessence, Inc. | 2024-01-18 | — | — | US | disclosed |
| US-11806448-B2 | Freshening compositions comprising controlled release modulators | Arylessence, Inc. (US) | 2023-11-07 | — | — | US | disclosed |
| CN-116103709-A | PCB through hole copper electroplating solution and preparation method thereof | 南通赛可特电子有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2023044460-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING HYDROXYMELONAL FORMATE ESTER | P2 SCIENCE, INC. (US) | 2023-03-23 | — | — | WO | disclosed |
| CN-115787053-A | High-stability electroplating additive and preparation method thereof | 南通赛可特电子有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-107428638-B | Fragrance and perfume compositions comprising neopentyl glycol diacetate | P2科学公司 | 2023-01-24 | — | — | CN | disclosed |
| US-20070092623-A1 | Food products containing a fruit component | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1689256-A1 | FOOD PRODUCTS CONTAINING A FRUIT COMPONENT | Takasago International Corporation (JP) | 2006-08-16 | — | — | EP | disclosed |
| US-20060165622-A1 | Deodorant composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-07-27 | — | — | US | disclosed |
| CN-1732019-A | Deodorant composition | TAKASAGO PERFUMERY CO LTD (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1561476-A1 | DEODORANT COMPOSITION | Takasago International Corporation (JP) | 2005-08-10 | — | — | EP | disclosed |
| WO-2005048743-A1 | FOOD PRODUCTS CONTAINING A FRUIT COMPONENT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-02 | — | — | WO | disclosed |
| JP-S6456798-A | LIQUID DETERGENT BLEACHING AGENT COMPOSITION HAVING AROMA | TAIYO KORYO KK | 1989-03-03 | — | — | JP | disclosed |