Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504016 | 0.85 | ALDH1A1 (0.48) | ALDH1A1AOC3CYP2C9CYP2C19HPGD | |
| SCHEMBL12742303 | 0.85 | KMT2A (0.45) | ALDH1A1AOC3CYP2C9CYP2C19HPGD | |
| SCHEMBL9711274 | 0.85 | AOC3 (0.44) | ALDH1A1AOC3CYP2C9CYP2C19HPGD | |
| SCHEMBL13557307 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP2C19HPGDHTT | |
| SCHEMBL18832093 | 0.84 | ALDH1A1 (0.41) | ALDH1A1AOC3CYP2C9CYP2C19HPGD | |
| SCHEMBL11556826 | 0.83 | FABP4 (0.49) | ALDH1A1FABP4FABP5HPGDHTT | |
| SCHEMBL1641813 | 0.83 | HPGD (0.46) | ALDH1A1AOC3CYP2C9CYP2C19HPGD | |
| SCHEMBL9711275 | 0.83 | AOC3 (0.45) | ALDH1A1AOC3CYP2C9CYP2C19HPGD | |
| SCHEMBL6929002 | 0.82 | NCEH1 (0.43) | ALDH1A1FABP4FABP5HPGDCYP1A2 | |
| SCHEMBL27771442 | 0.82 | HPGD (0.44) | ALDH1A1CYP2C9CYP2C19HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108535476-A | Ternary system Immune competition method detects the quantum dot immune chromatography detection card and detection method of naproxen | 韶关学院 | 2018-09-14 | — | — | CN | disclosed |
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | PURDUE RESEARCH FOUNDATION (US) | 2018-06-19 | — | — | US | disclosed |
| EP-3094613-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | Purdue Research Foundation, Inc. (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20160332940-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | PURDUE RESEARCH FOUNDATION (US) | 2016-11-17 | — | — | US | disclosed |
| WO-2015106045-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | PURDUE RESEARCH FOUNDATION (US) | 2015-07-16 | — | — | WO | disclosed |
| US-7910750-B2 | Aryl ethers of dihydroartemisnin such as 4-methoxycarbonylmethyl phenyl-dihydroartemisinine ether; immunosuppressants; dosage forms including tablets, ointments and suppositories; side effect reduction over cyclosporin A | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2011-03-22 | — | — | US | disclosed |
| US-20080139642-A1 | Artemisinin (Qinghaosu) Derivatives, Their Preparation Methods And Their Use, And Pharmaceutical Compositions Containing The Same | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-06-12 | — | — | US | disclosed |
| EP-0852494-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139642-A1 | Artemisinin (Qinghaosu) Derivatives, Their Preparation Methods And Their Use, And Pharmaceutical Compositions Containing The Same | THPO, CYP3A5, CYP3A43 | ALDH1A1 951/4885AOC3 4308/4885FABP4 3310/4885 |
| US-20160332940-A1 | PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS | CYP51A1, ALKBH3, ALKBH1 | ALDH1A1 500/4885AOC3 566/4885FABP4 2034/4885 |
| US-10000432-B2 | Processes for the synthesis of chiral 1-alkanols | CYP51A1, ALKBH3, ALKBH1 | ALDH1A1 500/4885AOC3 566/4885FABP4 2034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.