Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 8/20 | 0.41 |
| ▸ | CTSK | P43235 | 8/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729143 | 1.00 | CYP2C9 (0.44) | CYP2C9CYP2C19HDAC8CTSSCTSK | |
| SCHEMBL8729117 | 0.79 | HDAC8 (0.47) | HDAC8CTSSCTSKCTSLCTSB | |
| SCHEMBL5586793 | 0.77 | CTSK (0.49) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL8729106 | 0.77 | ADRB3 (0.49) | HDAC8CTSSCTSKCTSLCTSB | |
| SCHEMBL8729115 | 0.77 | ADRB3 (0.49) | HDAC8CTSSCTSKCTSLCTSB | |
| SCHEMBL8729119 | 0.75 | ACACB (0.49) | HDAC8PTPN1 | |
| SCHEMBL8732286 | 0.75 | ACACB (0.49) | HDAC8PTPN1 | |
| SCHEMBL8729003 | 0.75 | ACACB (0.49) | HDAC8PTPN1 | |
| SCHEMBL507002 | 0.75 | MTNR1A (0.66) | CTSSCTSKATMMTNR1AMTNR1B | |
| SCHEMBL507001 | 0.75 | MTNR1A (0.66) | CTSSCTSKATMMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |