Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732412 | 0.84 | CA2 (0.47) | NAMPTKMT2ACA1CA2CA12 | |
| SCHEMBL28463594 | 0.77 | NAMPT (0.49) | NAMPTKMT2ACA1CA2CA12 | |
| SCHEMBL8729155 | 0.76 | NAMPT (0.43) | NAMPTEPHX1KMT2AMEN1CA1 | |
| SCHEMBL27741033 | 0.75 | ACACB (0.59) | NAMPTKMT2ACA1CA2CA12 | |
| SCHEMBL8733934 | 0.74 | NAMPT (0.48) | NAMPTKMT2ACA1CA2CA12 | |
| SCHEMBL5892281 | 0.74 | CA1 (0.55) | NAMPTKMT2AMEN1CA1CA2 | |
| SCHEMBL1541945 | 0.74 | CA1 (0.64) | NAMPTKMT2AMEN1CA1CA2 | |
| SCHEMBL19003451 | 0.73 | ACACB (0.61) | NAMPTKMT2AMEN1CA1CA2 | |
| SCHEMBL26964370 | 0.73 | CA1 (0.56) | NAMPTKMT2ACA1CA2CA12 | |
| SCHEMBL4427701 | 0.73 | PTPN1 (0.52) | NAMPTKMT2ACA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |