Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728998 | 0.83 | CA2 (0.48) | NAMPTKMT2ACA1CA2CA12 | |
| SCHEMBL8733831 | 0.82 | ACACB (0.45) | — | |
| SCHEMBL8758157 | 0.79 | KMT2A (0.47) | EPHX1KMT2AMEN1ALDH1A1HRH3 | |
| SCHEMBL8729157 | 0.78 | ACACB (0.46) | CA1CA2CA12CA9 | |
| SCHEMBL28463594 | 0.78 | NAMPT (0.49) | NAMPTKMT2ACA1CA2CA12 | |
| SCHEMBL8230392 | 0.77 | GLA (0.47) | NAMPTKMT2ACA1CA2CA12 | |
| SCHEMBL8729156 | 0.76 | NAMPT (0.42) | NAMPTEPHX1KMT2AMEN1CA1 | |
| SCHEMBL27741033 | 0.76 | ACACB (0.59) | NAMPTKMT2ACA1CA2CA12 | |
| SCHEMBL23291146 | 0.75 | HRH3 (0.55) | HRH3 | |
| SCHEMBL23291176 | 0.75 | HRH3 (0.55) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |