Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | CA1 | P00915 | 3/20 | 0.68 |
| ▸ | CA9 | Q16790 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3000231 | 0.86 | ALDH1A1 (0.83) | ALDH1A1CA1CA9TP53KDM4E | |
| SCHEMBL2992964 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CA1CA9TP53KDM4E | |
| SCHEMBL16785428 | 0.82 | ALDH1A1 (0.76) | ALDH1A1CA1CA9TP53KDM4E | |
| SCHEMBL2998472 | 0.81 | CA1 (1.00) | ALDH1A1CA1CA9TP53KDM4E | |
| SCHEMBL5468686 | 0.80 | RAB9A (0.59) | ALDH1A1CA1CA9KDM4ECYP3A4 | |
| SCHEMBL2988323 | 0.79 | ALDH1A1 (0.86) | ALDH1A1CA1CA9TP53KDM4E | |
| SCHEMBL5464442 | 0.78 | APEX1 (0.52) | ALDH1A1CA1CA9KDM4EMPO | |
| SCHEMBL28701752 | 0.78 | KDM4E (0.53) | ALDH1A1CA1CA9TP53KDM4E | |
| SCHEMBL10652021 | 0.78 | ALDH1A1 (0.68) | ALDH1A1CA1CA9TP53KDM4E | |
| SCHEMBL2986200 | 0.78 | ALDH1A1 (0.83) | ALDH1A1CA1CA9TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750545-A | EXHIBIT EOSINOPHIL-INHIBITORY ACTION AND LYMPHOCYTE ACTIVATION-INHIBITORY ACTION; USEFUL FOR TREATMENT OF IMMUNE-RELATED DISEASES | THE GREEN CROSS CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0710654-A1 | TRIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-08 | — | — | EP | disclosed |